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Congenital diseases caused by defective O-glycosylation of Notch receptors

The Notch signaling pathway is highly conserved and essential for animal development. It is required for cell differentiation, survival, and proliferation. Regulation of Notch signaling is a crucial process for human health. Ligands initiate a signal cascade by binding to Notch receptors expressed o...

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Bibliographische Detailangaben
Veröffentlicht in:Nagoya J Med Sci
Hauptverfasser: Tashima, Yuko, Okajima, Tetsuya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nagoya University 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125653/
https://ncbi.nlm.nih.gov/pubmed/30214079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18999/nagjms.80.3.299
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