Biological Aspects of mTOR in Leukemia

The mammalian target of rapamycin (mTOR) is a central processor of intra- and extracellular signals, regulating many fundamental cellular processes such as metabolism, growth, proliferation, and survival. Strong evidences have indicated that mTOR dysregulation is deeply implicated in leukemogenesis....

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Mirabilii, Simone, Ricciardi, Maria Rosaria, Piedimonte, Monica, Gianfelici, Valentina, Bianchi, Maria Paola, Tafuri, Agostino
Format: Artigo
Language:Inglês
Published: MDPI 2018
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121663/
https://ncbi.nlm.nih.gov/pubmed/30110936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19082396
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