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STAT3 is a master regulator of epithelial identity and KRAS-driven tumorigenesis
A dichotomy exists regarding the role of signal transducer and activator of transcription 3 (STAT3) in cancer. Functional and genetic studies demonstrate either an intrinsic requirement for STAT3 or a suppressive effect on common types of cancer. These contrasting actions of STAT3 imply context depe...
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| Publicado no: | Genes Dev |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6120712/ https://ncbi.nlm.nih.gov/pubmed/30135074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.311852.118 |
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