A directed evolution approach to select for novel Adeno-associated virus capsids on an HIV-1 producer T cell line

A directed evolution approach was used to select for Adeno-associated virus (AAV) capsids that would exhibit more tropism toward an HIV-1 producer T cell line with the long-term goal of developing improved gene transfer vectors. A library of AAV variants was used to infect H9 T cells previously infe...

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Detaylı Bibliyografya
Yayımlandı:J Virol Methods
Asıl Yazarlar: Wooley, Dawn P., Sharma, Priyanka, Weinstein, John R., Narayan, Poornima Kotha Lakshmi, Schaffer, David V., Excoffon, Katherine J.D.A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6112236/
https://ncbi.nlm.nih.gov/pubmed/28918073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2017.09.008
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