Identification of Mycobacterial Ribosomal Proteins as Targets for CD4(+) T Cells That Enhance Protective Immunity in Tuberculosis

Mycobacterium tuberculosis remains a threat to global health, and a more efficacious vaccine is needed to prevent disease caused by M. tuberculosis. We previously reported that the mycobacterial ribosome is a major target of CD4(+) T cells in mice immunized with a genetically modified Mycobacterium...

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Veröffentlicht in:Infect Immun
Hauptverfasser: Kennedy, Steven C., Johnson, Alison J., Bharrhan, Sushma, Lindestam Arlehamn, Cecilia S., Xu, Jiayong, Garforth, Scott J., Chan, John, Jacobs, William R., Sette, Alessandro, Almo, Steven C., Porcelli, Steven A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105890/
https://ncbi.nlm.nih.gov/pubmed/29891545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00009-18
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