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Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge Amphimedon chloros with In Vitro Inhibitory Activity against the West Nile Virus NS3 Protease

Viruses are underrepresented as targets in pharmacological screening efforts, given the difficulties of devising suitable cell-based and biochemical assays. In this study we found that a pre-fractionated organic extract of the Red Sea sponge Amphimedon chloros was able to inhibit the West Nile Virus...

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Vydáno v:Molecules
Hlavní autoři: O’Rourke, Aubrie, Kremb, Stephan, Duggan, Brendan M., Sioud, Salim, Kharbatia, Najeh, Raji, Misjudeen, Emwas, Abdul-Hamid, Gerwick, William H., Voolstra, Christian R.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099703/
https://ncbi.nlm.nih.gov/pubmed/29912151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23061472
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