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Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge Amphimedon chloros with In Vitro Inhibitory Activity against the West Nile Virus NS3 Protease

Viruses are underrepresented as targets in pharmacological screening efforts, given the difficulties of devising suitable cell-based and biochemical assays. In this study we found that a pre-fractionated organic extract of the Red Sea sponge Amphimedon chloros was able to inhibit the West Nile Virus...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: O’Rourke, Aubrie, Kremb, Stephan, Duggan, Brendan M., Sioud, Salim, Kharbatia, Najeh, Raji, Misjudeen, Emwas, Abdul-Hamid, Gerwick, William H., Voolstra, Christian R.
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099703/
https://ncbi.nlm.nih.gov/pubmed/29912151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23061472
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