Oct4 regulates DNA methyltransferase 1 transcription by direct binding of the regulatory element

BACKGROUND: The transcription factor Oct4 plays a pivotal role in the pre-implantation development of the mouse embryo. DNA methyltransferase 1 (Dnmt1) maintains the changes in DNA methylation during mammalian early embryonic development. Little is known of the role of Oct4 in DNA methylation in mic...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Mol Biol Lett
Main Authors: Wu, Fengrui, Wu, Qingqing, Li, Dengkun, Zhang, Yuan, Wang, Rong, Liu, Yong, Li, Wenyong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097287/
https://ncbi.nlm.nih.gov/pubmed/30140294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-018-0104-2
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