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Modified translationally controlled tumor protein-derived protein transduction domain enhances nasal delivery of exendin-4 as shown with insulin

Protein transduction domains (PTDs) have been shown to promote the delivery of therapeutic proteins or peptides into the living cells. In a previous study, we showed that the double mutant of TCTP-PTD 13, TCTP-PTD 13M2, was more effective in the delivery of insulin than the wild-type TCTP-PTD 13. In...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Bae, Hae-Duck, Kim, Moonhee, Lee, Joohyun, Lee, Kyunglim
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096457/
https://ncbi.nlm.nih.gov/pubmed/30044154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1491653
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