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Challenges Associated With Applying Physiologically Based Pharmacokinetic Modeling for Public Health Decision-Making.

The development and application of physiologically based pharmacokinetic (PBPK) models in chemical toxicology have grown steadily since their emergence in the 1980s. However, critical evaluation of PBPK models to support public health decision-making across federal agencies has thus far occurred for...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Tan, YM, Worley, RR, Leonard, JA, Fisher, JW
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084449/
https://ncbi.nlm.nih.gov/pubmed/29385573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy010
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