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Mechanistic Insights Into MicroRNA-Induced Neuronal Reprogramming of Human Adult Fibroblasts

The use of transcriptional factors as cell fate regulators are often the primary focus in the direct reprogramming of somatic cells into neurons. However, in human adult fibroblasts, deriving functionally mature neurons with high efficiency requires additional neurogenic factors such as microRNAs (m...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Lu, Ya-Lin, Yoo, Andrew S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6083049/
https://ncbi.nlm.nih.gov/pubmed/30116172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00522
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