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TSC1 and DEPDC5 regulate HIV-1 latency through the mTOR signaling pathway

The latent reservoir of HIV-1 presents a major barrier to viral eradication. The mechanism of the establishment and maintenance of the latent viral reservoir is not yet fully understood, which hinders the development of effective curative strategies. In this study, we identified two inhibitory genes...

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Enregistré dans:
Détails bibliographiques
Publié dans:Emerg Microbes Infect
Auteurs principaux: Jin, Shan, Liao, Qibin, Chen, Jian, Zhang, Linxia, He, Qian, Zhu, Huanzhang, Zhang, Xiaoyan, Xu, Jianqing
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081400/
https://ncbi.nlm.nih.gov/pubmed/30087333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41426-018-0139-5
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