The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia

Primary cilia are crucial for signal transduction in a variety of pathways, including hedgehog and Wnt. Disruption of primary cilia formation (ciliogenesis) is linked to numerous developmental disorders (known as ciliopathies) and diseases, including cancer. The ubiquitin–proteasome system (UPS) com...

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Библиографические подробности
Опубликовано в: :Mol Biol Cell
Главные авторы: Shearer, Robert F., Frikstad, Kari-Anne Myrum, McKenna, Jessie, McCloy, Rachael A., Deng, Niantao, Burgess, Andrew, Stokke, Trond, Patzke, Sebastian, Saunders, Darren N.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2018
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080653/
https://ncbi.nlm.nih.gov/pubmed/29742019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-04-0248
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