The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia

Primary cilia are crucial for signal transduction in a variety of pathways, including hedgehog and Wnt. Disruption of primary cilia formation (ciliogenesis) is linked to numerous developmental disorders (known as ciliopathies) and diseases, including cancer. The ubiquitin–proteasome system (UPS) com...

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Pubblicato in:Mol Biol Cell
Autori principali: Shearer, Robert F., Frikstad, Kari-Anne Myrum, McKenna, Jessie, McCloy, Rachael A., Deng, Niantao, Burgess, Andrew, Stokke, Trond, Patzke, Sebastian, Saunders, Darren N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2018
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080653/
https://ncbi.nlm.nih.gov/pubmed/29742019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-04-0248
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