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The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia
Primary cilia are crucial for signal transduction in a variety of pathways, including hedgehog and Wnt. Disruption of primary cilia formation (ciliogenesis) is linked to numerous developmental disorders (known as ciliopathies) and diseases, including cancer. The ubiquitin–proteasome system (UPS) com...
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| Publicado en: | Mol Biol Cell |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Cell Biology
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6080653/ https://ncbi.nlm.nih.gov/pubmed/29742019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-04-0248 |
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