Evaluation of the safety and tolerability of tamoxifen for ischemia-incited renal injury in mice

Tamoxifen is used to activate tamoxifen-dependent Cre recombinase (CreER) to generate time- and tissue-specific genetically mutant mice. However, tamoxifen is also an active estrogen analogue that binds with higher affinity to estrogen receptors and exhibits anti-apoptosis, anti-inflammation, and an...

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Bibliografiske detaljer
Udgivet i:Am J Transl Res
Main Authors: Wang, Yuxi, Zhao, Zhi, Yang, Weiqi, Li, Lin, Zhu, Fengming, Pei, Guangchang, Yang, Juan, Zhu, Han, Xu, Huzi, Wang, Meng, Yang, Qian, Hu, Zhizhi, Wang, Pengge, Xu, Gang, Zeng, Rui, Yao, Ying
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2018
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079119/
https://ncbi.nlm.nih.gov/pubmed/30093955
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