Integrated Molecular Characterization of Testicular Germ Cell Tumors

We studied 137 primary testicular germ cell tumors (TGCTs) using high-dimensional assays of genomic, epigenomic, transcriptomic, and proteomic features. These tumors exhibited high aneuploidy and a paucity of somatic mutations. Somatic mutation of only three genes achieved significance—KIT, KRAS, an...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Shen, Hui, Shih, Juliann, Hollern, Daniel P., Wang, Linghua, Bowlby, Reanne, Tickoo, Satish K., Thorsson, Vésteinn, Mungall, Andrew J., Newton, Yulia, Hegde, Apurva M., Armenia, Joshua, Sánchez-Vega, Francisco, Pluta, John, Pyle, Louise C., Mehra, Rohit, Reuter, Victor E., Godoy, Guilherme, Jones, Jeffrey, Shelley, Carl S., Feldman, Darren R., Vidal, Daniel O., Lessel, Davor, Kulis, Tomislav, Cárcano, Flavio M., Leraas, Kristen M., Lichtenberg, Tara M., Brooks, Denise, Cherniack, Andrew D., Cho, Juok, Heiman, David I., Kasaian, Katayoon, Liu, Minwei, Noble, Michael S., Xi, Liu, Zhang, Hailei, Zhou, Wanding, ZenKlusen, Jean C., Hutter, Carolyn M., Felau, Ina, Zhang, Jiashan, Schultz, Nikolaus, Getz, Gad, Meyerson, Matthew, Stuart, Joshua M., Akbani, Rehan, Wheeler, David A., Laird, Peter W., Nathanson, Katherine L., Cortessis, Victoria K., Hoadley, Katherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6075738/
https://ncbi.nlm.nih.gov/pubmed/29898407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.05.039
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