Mutational Intratumor Heterogeneity is a Complex and Early Event in the Development of Adult T-cell Leukemia/Lymphoma

The clonal architecture of tumors plays a vital role in their pathogenesis and invasiveness; however, it is not yet clear how this clonality contributes to different malignancies. In this study we sought to address mutational intratumor heterogeneity (ITH) in adult T-cell leukemia/lymphoma (ATL). AT...

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Veröffentlicht in:Neoplasia
Hauptverfasser: Farmanbar, Amir, Firouzi, Sanaz, Makałowski, Wojciech, Kneller, Robert, Iwanaga, Masako, Utsunomiya, Atae, Nakai, Kenta, Watanabe, Toshiki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press 2018
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Original article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6074008/
https://ncbi.nlm.nih.gov/pubmed/30032036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.07.001
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