Loss of white matter integrity reflects tau accumulation in Alzheimer disease defined regions

OBJECTIVE: White matter (WM) projections were assessed from Alzheimer disease (AD) gray matter regions associated with β-amyloid (Aβ), tau, or neurodegeneration to ascertain relationship between WM structural integrity with Aβ and/or tau deposition. METHODS: Participants underwent diffusion tensor i...

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Pubblicato in:Neurology
Autori principali: Strain, Jeremy F., Smith, Robert X., Beaumont, Helen, Roe, Catherine M., Gordon, Brian A., Mishra, Shruti, Adeyemo, Babatunde, Christensen, Jon J., Su, Yi, Morris, John C., Benzinger, Tammie L.S., Ances, Beau M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070383/
https://ncbi.nlm.nih.gov/pubmed/29959265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000005864
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