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Chromatin loop anchors are associated with genome instability in cancer and recombination hotspots in the germline
BACKGROUND: Chromatin loops form a basic unit of interphase nuclear organization, with chromatin loop anchor points providing contacts between regulatory regions and promoters. However, the mutational landscape at these anchor points remains under-studied. Here, we describe the unusual patterns of s...
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| Publicado no: | Genome Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6066925/ https://ncbi.nlm.nih.gov/pubmed/30060743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1483-4 |
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