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Integrative analysis of single-cell genomics data by coupled nonnegative matrix factorizations

When different types of functional genomics data are generated on single cells from different samples of cells from the same heterogeneous population, the clustering of cells in the different samples should be coupled. We formulate this “coupled clustering” problem as an optimization problem and pro...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Duren, Zhana, Chen, Xi, Zamanighomi, Mahdi, Zeng, Wanwen, Satpathy, Ansuman T., Chang, Howard Y., Wang, Yong, Wong, Wing Hung
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065048/
https://ncbi.nlm.nih.gov/pubmed/29987051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805681115
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