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Genetic Modifiers of Neurodegeneration in a Drosophila Model of Parkinson’s Disease

Disease phenotypes can be highly variable among individuals with the same pathogenic mutation. There is increasing evidence that background genetic variation is a strong driver of disease variability in addition to the influence of environment. To understand the genotype–phenotype relationship that...

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Pubblicato in:Genetics
Autori principali: Lavoy, Sierra, Chittoor-Vinod, Vinita G., Chow, Clement Y., Martin, Ian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063243/
https://ncbi.nlm.nih.gov/pubmed/29907646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.301119
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