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Metabolomics as a tool to evaluate the toxicity of formulations containing amphotericin B, an antileishmanial drug

Amphotericin B (AmB) is a drug of choice against life-threatening systemic fungal infections and an alternative therapy for the treatment of all forms of leishmaniasis. It is known that AmB and its conventional formulation cause renal damage; however, the lipid formulations can reduce these effects....

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Bibliografiske detaljer
Udgivet i:Toxicol Res (Camb)
Main Authors: Santos, Délia C. M., Lima, Marta L., Toledo, Juliano S., Fernandes, Paula A., Aguiar, Marta M. G., López-Gonzálvez, Ángeles, Ferreira, Lucas A. M., Fernandes, Ana Paula, Barbas, Coral
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062298/
https://ncbi.nlm.nih.gov/pubmed/30090471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6tx00253f
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