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Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2
Proteins in the fibrous amyloid state are a major hallmark of neurodegenerative disease. Understanding the multiple conformations, or polymorphs, of amyloid proteins at the molecular level is a challenge of amyloid research. Here, we detail the wide range of polymorphs formed by a segment of human T...
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| Publicado no: | Nat Struct Mol Biol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6056015/ https://ncbi.nlm.nih.gov/pubmed/29531287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0045-5 |
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