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The spinal NR2BR/ERK2 pathway as a target for the central sensitization of collagen-induced arthritis pain

OBJECTIVE: Pain management is a huge challenge in the treatment of rheumatoid arthritis (RA), and central sensitization is reportedly involved in the development of pain. The current study was undertaken to explore the possible role of N-methyl-D-aspartate receptors (NMDARs) in the spinal mechanism...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Xu, Yingming, Zhang, Kui, Miao, Jinlin, Zhao, Peng, Lv, Minghua, Li, Jia, Fu, Xianghui, Luo, Xing, Zhu, Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053233/
https://ncbi.nlm.nih.gov/pubmed/30024967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201021
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