The spinal NR2BR/ERK2 pathway as a target for the central sensitization of collagen-induced arthritis pain

OBJECTIVE: Pain management is a huge challenge in the treatment of rheumatoid arthritis (RA), and central sensitization is reportedly involved in the development of pain. The current study was undertaken to explore the possible role of N-methyl-D-aspartate receptors (NMDARs) in the spinal mechanism...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Xu, Yingming, Zhang, Kui, Miao, Jinlin, Zhao, Peng, Lv, Minghua, Li, Jia, Fu, Xianghui, Luo, Xing, Zhu, Ping
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053233/
https://ncbi.nlm.nih.gov/pubmed/30024967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201021
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