The spinal NR2BR/ERK2 pathway as a target for the central sensitization of collagen-induced arthritis pain

OBJECTIVE: Pain management is a huge challenge in the treatment of rheumatoid arthritis (RA), and central sensitization is reportedly involved in the development of pain. The current study was undertaken to explore the possible role of N-methyl-D-aspartate receptors (NMDARs) in the spinal mechanism...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Xu, Yingming, Zhang, Kui, Miao, Jinlin, Zhao, Peng, Lv, Minghua, Li, Jia, Fu, Xianghui, Luo, Xing, Zhu, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053233/
https://ncbi.nlm.nih.gov/pubmed/30024967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201021
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