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Optimization and comparison of CD4-targeting lipid–polymer hybrid nanoparticles using different binding ligands

Monoclonal antibodies and peptides are conjugated to the surface of nanocarriers (NCs) for targeting purposes in numerous applications. However, targeting efficacy may vary with their specificity, affinity, or avidity when linked to NCs. The physicochemical properties of NCs may also affect targetin...

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Bibliographic Details
Published in:J Biomed Mater Res A
Main Authors: Cao, Shijie, Jiang, Yonghou, Levy, Claire N., Hughes, Sean M., Zhang, Hangyu, Hladik, Florian, Woodrow, Kim A.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038932/
https://ncbi.nlm.nih.gov/pubmed/29271128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.36315
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