Differential expression of hsa-miR-221, hsa-miR-21, hsa-miR-135b, and hsa-miR-29c suggests a field effect in oral cancer

BACKGROUND: The theory of field effect suggests that the tumor-adjacent area, besides histopathologically normal, undergoes genetic and epigenetic changes that can eventually affect epithelial homeostasis, predisposing the patient to cancer development. One of the many molecular changes described in...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Lopes, Camile B., Magalhães, Leandro L., Teófilo, Carolina R., Alves, Ana Paula N. N., Montenegro, Raquel C., Negrini, Massimo, Ribeiro-dos-Santos, Ândrea
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034275/
https://ncbi.nlm.nih.gov/pubmed/29976158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4631-z
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