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Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans

Misfolding and accumulation of cellular protein aggregates are pathological hallmarks of aging and neurodegeneration. One such protein is α-synuclein, which when misfolded, forms aggregates and disrupts normal cellular functions of the neurons causing Parkinson’s disease. Nutritional interventions a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Maulik, Malabika, Mitra, Swarup, Hunter, Skyler, Hunstiger, Moriah, Oliver, S. Ryan, Bult-Ito, Abel, Taylor, Barbara E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033853/
https://ncbi.nlm.nih.gov/pubmed/29976995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26905-4
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