Inducible T-Cell Co-Stimulator Impacts Chronic Graft-Versus-Host Disease by Regulating Both Pathogenic and Regulatory T Cells

The incidence of chronic graft-versus-host disease (cGVHD) is on the rise and still the major cause of morbidity and mortality among patients after allogeneic hematopoietic stem cell transplantation (HCT). Both donor T and B cells contribute to the pathogenesis of cGVHD. Inducible T-cell co-stimulat...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Zhang, Mengmeng, Wu, Yongxia, Bastian, David, Iamsawat, Supinya, Chang, Jinsam, Daenthanasanmak, Anusara, Nguyen, Hung D., Schutt, Steven, Dai, Min, Chen, Fangping, Suh, Woong-Kyung, Yu, Xue-Zhong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023972/
https://ncbi.nlm.nih.gov/pubmed/29988391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01461
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