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Personalizing Polymyxin B Dosing Using an Adaptive Feedback Control Algorithm
Polymyxin B is used as an antibiotic of last resort for patients with multidrug-resistant Gram-negative bacterial infections; however, it carries a significant risk of nephrotoxicity. Herein we present a polymyxin B therapeutic window based on target area under the concentration-time curve (AUC) val...
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| Vydáno v: | Antimicrob Agents Chemother |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6021635/ https://ncbi.nlm.nih.gov/pubmed/29760144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00483-18 |
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