H3K27 acetylation and gene expression analysis reveals differences in placental chromatin activity in fetal growth restriction

BACKGROUND: Posttranslational modification of histone tails such as histone 3 lysine 27 acetylation (H3K27ac) is tightly coupled to epigenetic regulation of gene expression. To explore whether this is involved in placenta pathology, we probed genome-wide H3K27ac occupancy by chromatin immunoprecipit...

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Udgivet i:Clin Epigenetics
Main Authors: Paauw, N. D., Lely, A. T., Joles, J. A., Franx, A., Nikkels, P. G., Mokry, M., van Rijn, B. B.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020235/
https://ncbi.nlm.nih.gov/pubmed/29983832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0508-x
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