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Green light-induced apoptosis in cancer cells by a tetrapyridyl ruthenium prodrug offering two trans coordination sites

In this work, two new photopharmacological ruthenium prodrugs are described that can be activated by green light. They are based on the tetrapyridyl biqbpy ligand (6,6′-bis[N-(isoquinolyl)-1-amino]-2,2′-bipyridine), which coordinates to the basal plane of the metal centre and leaves two trans coordi...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: van Rixel, V. H. S., Siewert, B., Hopkins, S. L., Askes, S. H. C., Busemann, A., Siegler, M. A., Bonnet, Sylvestre
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018302/
https://ncbi.nlm.nih.gov/pubmed/30155140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00167j
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