Investigation into Improving the Aqueous Solubility of the Thieno[2,3-b]pyridine Anti-Proliferative Agents

It is now established that the thieno[2,3-b]pyridines are a potent class of antiproliferatives. One of the main issues encountered for their clinical application is their low water solubility. In order to improve this, two strategies were pursued. First, a morpholine moiety was tethered to the molec...

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Detaylı Bibliyografya
Yayımlandı:Molecules
Asıl Yazarlar: Zafar, Ayesha, Pilkington, Lisa I., Haverkate, Natalie A., van Rensburg, Michelle, Leung, Euphemia, Kumara, Sisira, Denny, William A., Barker, David, Alsuraifi, Ali, Hoskins, Clare, Reynisson, Jóhannes
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017400/
https://ncbi.nlm.nih.gov/pubmed/29324695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23010145
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