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pDCs in lung and skin fibrosis in a bleomycin-induced model and patients with systemic sclerosis

Fibrosis is the end result of most inflammatory conditions, but its pathogenesis remains unclear. We demonstrate that, in animals and humans with systemic fibrosis, plasmacytoid DCs (pDCs) are unaffected or are reduced systemically (spleen/peripheral blood), but they increase in the affected organs...

詳細記述

保存先:
書誌詳細
出版年:JCI Insight
主要な著者: Kafaja, Suzanne, Valera, Isela, Divekar, Anagha A., Saggar, Rajan, Abtin, Fereidoun, Furst, Daniel E., Khanna, Dinesh, Singh, Ram Raj
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012518/
https://ncbi.nlm.nih.gov/pubmed/29720568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98380
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