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VEGF/VEGFR2 blockade does not cause retinal atrophy in AMD-relevant models

Intraocular injections of VEGF-neutralizing proteins provide tremendous benefits in patients with choroidal neovascularization (NV) due to age-related macular degeneration (AMD), but during treatment some patients develop retinal atrophy. Suggesting that VEGF is a survival factor for retinal neurons...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Long, Da, Kanan, Yogita, Shen, Jikui, Hackett, Sean F., Liu, Yuanyuan, Hafiz, Zibran, Khan, Mahmood, Lu, Lili, Campochiaro, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012504/
https://ncbi.nlm.nih.gov/pubmed/29769445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120231
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