Antileishmanial activity of sulphonamide nanoemulsions targeting the β-carbonic anhydrase from Leishmania species

The β-carbonic anhydrase (CA, EC 4.2.1.1) from Leishmania spp. (LdcCA) is effectively inhibited by aromatic/heterocyclic sulphonamides, in the low nanomolar range, but no in vitro antileishmanial activity was detected for such compounds. We formulated some of these sulphonamides as nanoemulsions (NE...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:J Enzyme Inhib Med Chem
Main Authors: da Silva Cardoso, Verônica, Vermelho, Alane Beatriz, Ricci Junior, Eduardo, Almeida Rodrigues, Igor, Mazotto, Ana Maria, Supuran, Claudiu T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2018
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010131/
https://ncbi.nlm.nih.gov/pubmed/29708476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1463221
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla