Cancer stem cells CD133 inhibition and cytotoxicity of certain 3-phenylthiazolo[3,2-a]benzimidazoles: design, direct synthesis, crystal study and in vitro biological evaluation

Cancer stem cells (CSCs) have been objects of intensive study since their identification in 1994. Adopting a structural rigidification approach, a novel series of 3-phenylthiazolo[3,2-a]benzimidazoles 4a–d was designed and synthesised, in an attempt to develop potent anticancer agent that can target...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Al-Ansary, Ghada H., Eldehna, Wagdy M., Ghabbour, Hazem A., Al-Rashood, Sara T. A., Al-Rashood, Khalid A., Eladwy, Radwa A., Al-Dhfyan, Abdullah, Kabil, Maha M., Abdel-Aziz, Hatem A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010115/
https://ncbi.nlm.nih.gov/pubmed/28726519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1347166
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