One-pot three-component synthesis of novel spirooxindoles with potential cytotoxic activity against triple-negative breast cancer MDA-MB-231 cells

Triple-negative breast cancer (TNBC) is a highly aggressive malignancy with limited treatment options due to its heterogeneity and the lack of well-defined molecular targets. In our endeavour towards the development of novel anti-TNBC agents, herein we report a one-pot three-component synthesis of n...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Principais autores: Eldehna, Wagdy M., EL-Naggar, Dina H., Hamed, Ahmed R., Ibrahim, Hany S., Ghabbour, Hazem A., Abdel-Aziz, Hatem A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009943/
https://ncbi.nlm.nih.gov/pubmed/29281924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1417276
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