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DNA silencing by prokaryotic Argonaute proteins adds a new layer of defense against invading nucleic acids

Argonaute (Ago) proteins are encoded in all three domains of life and are responsible for the regulation of intracellular nucleic acid levels. Whereas some Ago variants are able to cleave target nucleic acids by their endonucleolytic activity, others only bind to their target nucleic acids while tar...

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Detalhes bibliográficos
Publicado no:FEMS Microbiol Rev
Main Authors: Willkomm, Sarah, Makarova, Kira S, Grohmann, Dina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995195/
https://ncbi.nlm.nih.gov/pubmed/29579258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femsre/fuy010
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