Intermittent fasting uncovers and rescues cognitive phenotypes in PTEN neuronal haploinsufficient mice

Phosphatase and tensin homolog (PTEN) is an important protein with key modulatory functions in cell growth and survival. PTEN is crucial during embryogenesis and plays a key role in the central nervous system (CNS), where it directly modulates neuronal development and synaptic plasticity. Loss of PT...

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Publicat a:Sci Rep
Autors principals: Cabral-Costa, J. V., Andreotti, D. Z., Mello, N. P., Scavone, C., Camandola, S., Kawamoto, E. M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988674/
https://ncbi.nlm.nih.gov/pubmed/29872062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26814-6
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