Xenon-inhibition of the MscL mechano-sensitive channel and the CopB copper ATPase under different conditions suggests direct effects on these proteins

Xenon is frequently used as a general anesthetic in humans, but the mechanism remains an issue of debate. While for some membrane proteins, a direct interaction of xenon with the protein has been shown to be the inhibitory mechanism, other membrane protein functions could be affected by changes of m...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Petrov, Evgeny, Menon, Gopalakrishnan, Rohde, Paul R., Battle, Andrew R., Martinac, Boris, Solioz, Marc
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986136/
https://ncbi.nlm.nih.gov/pubmed/29864148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198110
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