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Genome-wide DNA methylation patterns of bovine blastocysts derived from in vivo embryos subjected to in vitro culture before, during or after embryonic genome activation

BACKGROUND: Aberrant DNA methylation patterns of genes required for development are common in in vitro produced embryos. In this regard, we previously identified altered DNA methylation patterns of in vivo developed blastocysts from embryos which spent different stages of development in vitro, indic...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Salilew-Wondim, Dessie, Saeed-Zidane, Mohammed, Hoelker, Michael, Gebremedhn, Samuel, Poirier, Mikhaël, Pandey, Hari Om, Tholen, Ernst, Neuhoff, Christiane, Held, Eva, Besenfelder, Urban, Havlicek, Vita, Rings, Franca, Fournier, Eric, Gagné, Dominic, Sirard, Marc-André, Robert, Claude, Gad, Ahmed, Schellander, Karl, Tesfaye, Dawit
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984773/
https://ncbi.nlm.nih.gov/pubmed/29859035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-4826-3
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