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Genome-wide DNA methylation patterns of bovine blastocysts derived from in vivo embryos subjected to in vitro culture before, during or after embryonic genome activation

BACKGROUND: Aberrant DNA methylation patterns of genes required for development are common in in vitro produced embryos. In this regard, we previously identified altered DNA methylation patterns of in vivo developed blastocysts from embryos which spent different stages of development in vitro, indic...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Salilew-Wondim, Dessie, Saeed-Zidane, Mohammed, Hoelker, Michael, Gebremedhn, Samuel, Poirier, Mikhaël, Pandey, Hari Om, Tholen, Ernst, Neuhoff, Christiane, Held, Eva, Besenfelder, Urban, Havlicek, Vita, Rings, Franca, Fournier, Eric, Gagné, Dominic, Sirard, Marc-André, Robert, Claude, Gad, Ahmed, Schellander, Karl, Tesfaye, Dawit
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984773/
https://ncbi.nlm.nih.gov/pubmed/29859035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-4826-3
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