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Unmasking the skiptic task of TDP‐43

The mechanism by which mutations in TAR DNA‐binding protein 43 (TDP‐43) cause neurodegeneration remains incompletely understood. In this issue of The EMBO Journal, Fratta et al (2018) describe how a point mutation in the C‐terminal low complexity domain of TDP‐43 leads to the skipping of otherwise c...

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Publicat a:EMBO J
Autors principals: Rouaux, Caroline, Gonzalez De Aguilar, Jose‐Luis, Dupuis, Luc
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983166/
https://ncbi.nlm.nih.gov/pubmed/29769403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899645
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