Organic osmolytes preserve the function of the developing tight junction in ultraviolet B-irradiated rat epidermal keratinocytes

Epidermal barrier function is provided by the highly keratinised stratum corneum and also by tight junctions (TJs) in the granular layer of skin. The development of the TJ barrier significantly deteriorates in response to ultraviolet B radiation (UVB). Following exposure to UVB, keratinocytes accumu...

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Bibliographic Details
Published in:Sci Rep
Main Authors: El-Chami, Cécile, Haslam, Iain S., Steward, Martin C., O’Neill, Catherine A.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979960/
https://ncbi.nlm.nih.gov/pubmed/29581434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22533-0
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