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Assembly and Functional Analysis of an S/MAR Based Episome with the Cystic Fibrosis Transmembrane Conductance Regulator Gene

Improving the efficacy of gene therapy vectors is still an important goal toward the development of safe and efficient gene therapy treatments. S/MAR (scaffold/matrix attached region)-based vectors are maintained extra-chromosomally in numerous cell types, which is similar to viral-based vectors. Ad...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: De Rocco, Davide, Pompili, Barbara, Castellani, Stefano, Morini, Elena, Cavinato, Luca, Cimino, Giuseppe, Mariggiò, Maria A, Guarnieri, Simone, Conese, Massimo, Del Porto, Paola, Ascenzioni, Fiorentina
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979583/
https://ncbi.nlm.nih.gov/pubmed/29673202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041220
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