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C5a Blockade Increases Regulatory T Cell Numbers and Protects Against Microvascular Loss and Epithelial Damage in Mouse Airway Allografts
Microvascular injury during acute rejection has been associated with massive infiltration of CD4(+) T effector cells, and the formation of complement products (C3a and C5a). Regulatory T cells (Tregs) are potent immunosuppressors of the adaptive immune system and have proven sufficient to rescue mic...
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| Udgivet i: | Front Immunol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5976734/ https://ncbi.nlm.nih.gov/pubmed/29881374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01010 |
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