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3H-pyrazolo[4,3-f]quinoline haspin kinase inhibitors and anticancer properties

Histone modification, a post-translational modification of histones and involving various covalent tags, such as methyl, phosphate and acetate groups, affects gene expression and hence modulates various cellular events, including growth and proliferation. Consequently histone-modifying proteins have...

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Bibliographic Details
Published in:Bioorg Chem
Main Authors: Opoku-Temeng, Clement, Dayal, Neetu, Sooreshjani, Moloud Aflaki, Sintim, Herman O.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972072/
https://ncbi.nlm.nih.gov/pubmed/29698892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2018.03.031
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